ARDIA PRECISION HEALTHGoverned AI for healthcare revenue & precision care
Dallas-Fort Worth, Texas  ·  Founded Dec 2025

Governed AI for the work that
quietly drains labs & care teams

Precision Revenue Intelligence & Precision Care — for labs, specialty practices & value-based care

Ardia builds governed, auditable AI — the TARA reasoning core and a constellation of specialised models — for the jobs that drain labs and care teams: recovering wrongly denied lab revenue, modelling the 2027 PAMA cliff, and supporting precision medicine, pulmonary and elder care. Pre-revenue, seed-stage — every figure is measured, cited, or a modelled target.

$12BLab Revenue Left Unpaid · industry est.
35.3%Molecular Dx Denial · XiFin 2024
65%Denials Never Appealed · industry est.
45%Manual Appeal Success · HFMA 2024
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$3.8B in lab revenue cut by PAMA since 2018
35.3% average molecular claim denial rate (XiFin 2024)
80%+ of tox billing errors from documentation failures
$4.1B MSSP shared savings in 2024
$70B+ AI in RCM by 2030 · 24% CAGR
12,294 ASCs nationally · 57.9% physician-owned
$70B+ AI-in-RCM market by 2030 (Grand View 2024)
$3,000 per member/year from missed HCC codes
$3.8B in lab revenue cut by PAMA since 2018
35.3% average molecular claim denial rate (XiFin 2024)
80%+ of tox billing errors from documentation failures
$4.1B MSSP shared savings in 2024
$70B+ AI in RCM by 2030 · 24% CAGR
12,294 ASCs nationally · 57.9% physician-owned
$70B+ AI-in-RCM market by 2030 (Grand View 2024)
$3,000 per member/year from missed HCC codes

The Only AI Built for
Healthcare Revenue Recovery

We're not a billing software. We're not an alert system. We're a clinical reasoning engine that understands payer logic from the inside.

Clinical Reasoning, Not Alerts

Our engine reads clinical documentation, cross-references payer-specific LCD rules, and generates a mechanistic explanation for every denial — then builds the evidence-backed recovery argument.

Payer-Side Insider Knowledge

Engineering and operating roles inside Cigna, UnitedHealth Group, Optum, Teladoc, Interwell Health and ECFMG. We've built within the payer systems that construct coverage and denial decisions — so we know the adjudication logic from the inside, and exactly how to reverse it.

Zero-Risk Contingency Model

We earn 15–20% of recovered revenue only when you succeed. No upfront cost. No implementation fees. ROI is designed to surface within ~30 days of deployment — a modelled target, pre-pilot.

Automating the $118 Manual Appeal

Manual appeals cost $118 and succeed 45% of the time on average — industry benchmarks (Change Healthcare 2023, HFMA 2024). Ardia automates that costly manual process end-to-end: grounded in policy and the patient record, with practitioner review before submission.

Precision Medicine + Revenue

The only platform combining genomic intelligence with reimbursement intelligence. We make precision medicine economically sustainable — MolDX, Z-codes, and 400+ PLA codes.

Building on Google Cloud Platform

Planned under BAA: HIPAA-eligible GCP services — Vertex AI, Cloud Healthcare API (FHIR R4), BigQuery, Cloud Run. Target: US data residency (us-central1), AES-256 at rest, TLS 1.3 in transit. The current prototype runs on Vercel + Anthropic Claude.

Full Story: Why Ardia is Different
What we're building · explore each

Solutions, models & real-time demos

The areas Ardia is focused on today — click any card to go deep. Pre-revenue; every figure is measured, cited, or a modelled target.

Aging & Elder Care
Aria + Cadence

AI for the aging population — Aria (voice companion, red-flag safety check, 911 escalation) and Cadence, the trained movement model (95.45% held-out on public UCI HAR data), plus the elder-care modules.

Explore →
Pulmonary Care
PulmoIQ

Longitudinal asthma & COPD intelligence — aligned to GOLD and GINA staging concepts (guideline retrieval corpus in development), with pulmonary-function and sleep-study coding integrity. Decision-support, non-diagnostic.

Explore →
PAMA Rate-Cliff
Meridian

A deterministic, in-browser model of the 2027–2029 CLFS cuts and the exact revenue at risk for your test mix. No PHI; the compounding math is unit-tested.

Explore →
Precision Medicine
MolecuIQ · genomics

Personalise each patient's care — the right drug & dose (pharmacogenomics), therapy matched to the molecular target, inherited risk caught early. Plus the access layer that gets the enabling tests covered.

Explore →
Lab Reimbursement
ToxIQ + MolecuIQ

Policy-grounded, cited denial appeals for toxicology & molecular billing — G0480–G0483, NCCI edits, CARC/RARC. Drafts for a human to review and submit.

Explore →
All Models & Agents
the full roster

Every model and agent in one place — Lumen, Aria, MolecuIQ, ToxIQ, PulmoIQ, Cadence, TARA, Meridian, Sentinel — each with its AI engine, frameworks, and honest status.

Explore →
Watch the 2-minute demo Watch every model reason — real-time demos See the measured test results
◆ 2-minute walkthrough

See Ardia in action

A quick tour of the governed models and the Ardia One care hub — de-identified inputs, cite-or-abstain answers, and a unified elder-first experience. Synthetic data; Ardia is pre-revenue.

Try Ardia One (guest) Watch a model reason

Illustrative walkthrough on synthetic data — not a diagnosis, and not real patient information.

Agents · real-time, governed interaction

The agents doing the work

Nine named models and agents — each does one job well, all share one governed core (TARA reasoning + Sentinel de-identification). Click any to watch it reason through a real case. Pre-revenue: every status is measured, cited, or a modelled target.

Aria
Voice companion & safety spine

A voice-first companion for older adults — daily check-ins, medication support, a red-flag safety check (stroke FAST, suicide C-SSRS), and 911 escalation. Talks in real time; never diagnoses.

Claude / Gemini persona · guardrails Modelled target
Watch it reason →
Lumen
Plain-language report explainer

Turns a lab report or scan into plain language a patient can act on — flags what stands out, names what to confirm, explains options. De-identified first by Sentinel. Non-diagnostic.

Claude / Gemini persona · de-identified first Modelled target
Watch it reason →
MolecuIQ
Molecular & genomic denial recovery

Reads a denied molecular/genomic claim and drafts a cited appeal — NGS panels (81445/81455), MolDX Z-codes, CO-50 medical-necessity. A human reviews and submits; never auto-filed.

Claude / Gemini persona Modelled target
Watch it reason →
ToxIQ
Toxicology denial appeals

Turns a denied toxicology claim into a policy-cited appeal — G0480–G0483, NCCI edits, CARC/RARC — with a PGx overlay explaining unexpected negative screens. Drafted for a human to submit.

Claude / Gemini persona Modelled target
Watch it reason →
PulmoIQ
Respiratory intelligence

Builds a longitudinal asthma/COPD picture against GOLD & GINA and supports PFT and sleep-study reimbursement. Anything that predicts disease stays behind FDA clearance.

Claude / Gemini persona Modelled target
Watch it reason →
TARA
The governed reasoning core

The Triadic Adjudicative Reasoning core every agent runs on — a deterministic policy engine plus a guarded LLM that cannot override policy or safety. Always human-in-the-loop, always auditable.

Neuro-symbolic reasoning architecture Framework · in build
Watch it reason →
Cadence
Movement & deterioration model

The one genuinely trained & measured model — senses the earliest drop in daily movement from a phone. 95.45% held-out on public UCI HAR, subject-independent. Not a fall detector.

scikit-learn classifier Measured · 95.45%
Watch it reason →
Meridian
PAMA rate-cliff engine

A deterministic, in-browser model of the 2027–2029 PAMA rate cliff — enter a test mix and watch the revenue at risk compound. No PHI, no server; the math is unit-tested.

Deterministic engine · no LLM Deterministic · unit-tested
Watch it reason →
Sentinel
The compliance kernel

The compliance kernel — de-identifies every record to HIPAA Safe Harbor before any agent runs, and logs a tamper-evident audit trail. A guardrail the others depend on, not a feature.

Rule-based de-identification In build
Watch it reason →
Watch every agent reason in real time Explore the full roster & engines

Why Ardia Wins Where Others Fail

The RCM space is crowded with alerting tools, billing software, and generic AI. Ardia is the only platform that reasons, argues, and proves — built by people who designed the denial systems it defeats.

Capability Quest / LabCorp RCM Generic AI (Olive, Waystar) Traditional RCM Vendors ⚡ Ardia Precision Health
✓ = designed / in build, not yet shipped
Clinical Reasoning (not just flagging)
Lab-Specific Denial Logic (LCD/NCD)
Partial
Auto-Generated Appeal Narratives
Generic only
Pharmacogenomics + MolDX Reimbursement
Zero-Risk Contingency Pricing
Rare
TX SB 1188 + TRAIGA Compliant by Design
Built by Former Payer Insiders (Cigna/UHC)
🧠
Insider Intelligence
Engineering roles inside Cigna, UnitedHealth Group, Optum and Teladoc — we've built within the payer systems that generate denials, and we know the adjudication logic from the inside. No other AI vendor has this advantage.
⚖️
Financial Adversary Engine
We don't alert you — we argue your case. Every appeal includes clinical citations, LCD cross-references, and a mechanistic proof of medical necessity.
🧬
Precision + Revenue Together
The only platform combining genomic intelligence with reimbursement logic. PGx, MolDX, Z-codes, 400+ PLA codes — all in one engine.
🛡️
Zero-Risk. Pay on Recovery.
15–20% contingency only when you recover. No upfront costs. No implementation fees. ROI modelled to surface in ~30 days. If we don't win, you don't pay.

End-to-End: From Denied Claim
to Recovered Revenue

Six decision-support steps, each reviewed by a licensed professional before anything is submitted. No template letters. Clinical reasoning powered by AI at every stage — from raw denial data to a payer-formatted appeal draft — a design target of under 90 seconds per claim.

1
Data Ingestion
Claim & Denial Intake
835/837 EDI denial files ingested via API, SFTP, or direct upload. Target throughput: 1,000+ claims parsed per minute. No EHR integration required for Phase 1.
ANSI X12 835837P/ISFTP / API
2
Rules Engine
Payer Rules Activation
Engine identifies exact MAC jurisdiction, applicable LCD/NCD, and denial reason code. 400+ payer policies. Updated weekly via CMS feeds.
All 7 MACsMolDXLCD/NCD
3
AI Clinical Reasoning
Document Analysis & Gap Detection
Claude AI (Anthropic) reads clinical notes, Rx, lab results, and genomic reports — then reasons against the payer's specific medical necessity criteria and pinpoints exactly what's missing.
Claude AIFHIR R4NLPHL7
4
Evidence Generation
Appeal Package Assembly
Complete appeal letter with clinical argument, LCD citations, NCCN/ASCO guideline references, and supporting documentation — formatted to the payer's exact requirements.
NCCN / ASCOAHA / ACC< 90 sec
5
Workflow & Submission
Review Queue & Direct Submission
Prioritized reviewer queue by recovery amount and deadline. One-click submission to the clearinghouse only after explicit reviewer approval, with physician attestation on every appeal.
ClearinghouseReviewer-Approved Submit
6
Analytics & Learning
ROI Tracking & Continuous Learning
Every outcome tracked — paid, denied, adjusted. A modelled ROI dashboard (concept). Successful appeals continuously refine reasoning models. Systemic denial patterns identified and exploited over time.
Real-time ROIPattern DetectionML Feedback
< 90 sec
Full Appeal Generated
15%
Contingency · on recovery
$118
Avg Manual Appeal Cost
30 days
Time to First ROI · modelled target
Full Technical Process Details

A $70B+ Market with No AI-Native
Incumbent for Independent Labs

The AI in RCM market grows at 24% CAGR. Independent labs are completely unserved.

📉
$3.8B
Lab Revenue Cut by PAMA
Since 2018 · CMS CLFS reductions
🧬
$3.4B
Molecular Revenue at Risk
Annual denials & write-offs
💊
$70B+
AI in RCM Market by 2030
24% CAGR · Grand View Research 2024
🏥
~$12B
Independent-Lab Revenue Lost/Year
To documentation gaps, not fraud
See Full Market Analysis & Investor Materials
Precision Medicine & Genomic Care

The right care, matched to the person

Precision medicine uses a patient's own genomic and molecular profile to personalise prevention and treatment — the right drug and dose, therapy matched to a tumour's biology, and inherited risk caught early. Ardia is building the decision-support for that, and the access layer (MolecuIQ, today) that gets the enabling tests covered so cost isn't what blocks a patient.

$120B
Precision Med TAM (2025)
Projected $250B by 2030
35.3%
Molecular Dx Denial Rate
XiFin 2024 · 20M+ claims analyzed
2.76×
Higher Denial for Ind. Labs
vs. hospital labs · JAMA 2025 n=29,919
75K+
Genetic Tests, <200 CPT Codes
Root cause of precision med denials
🧬

Inherited risk, caught early

Flags pathogenic hereditary variants — BRCA1/2, Lynch — with ACMG classification, then points to personalised screening, risk-reducing prevention and family cascade testing. Preventing disease, not only treating it.

💊

Right drug, right dose

Reads the patient's own pharmacogenomics — CYP2C19, CYP2D6, DPYD, TPMT, HLA-B — to flag drug–gene risks and guide a safer choice and dose (CPIC), avoiding adverse reactions and medications that won't work for them. Non-diagnostic decision-support.

🔬

Therapy matched to the molecular target

Interprets a tumour's molecular profile — EGFR, ALK, BRAF, KRAS, MSI-H/TMB — and surfaces NCCN-guideline targeted therapies, immunotherapy and open trials to support the oncologist's personalised plan.

⚗️

A longitudinal precision-health picture

Brings genomic, molecular, clinical and lifestyle signals into one evolving, personalised risk-and-prevention view — including liquid-biopsy and ctDNA monitoring for earlier detection and response tracking.

🛡️

Grounded, auditable reasoning

Coverage and clinical-guideline policies (CPIC, NCCN, LCD/NCD, MolDX) are encoded as deterministic rules, so every recommendation traces to a named source rather than a black box. Being built.

📄

Access & coverage — so patients aren't blocked

MolDX/Z-code validation, medical-necessity documentation and cited appeals get the enabling molecular test paid — the plumbing that makes the personalised answer reachable. MolecuIQ drafts; a human reviews and submits.

Full Precision Medicine Platform All Solutions
Products & Development Stage

Where Ardia is focused right now

The models we're building today — across lab reimbursement (ToxIQ, MolecuIQ), precision medicine (genomics & pharmacogenomics), the PAMA rate cliff (Meridian), pulmonary care (PulmoIQ), elder care (Aria + Cadence), and plain-language reports (Lumen) — each running on the TARA reasoning core and the Sentinel compliance kernel.

Pre-Revenue · Seed Stage DFW Pilot Target: Q2 2026 Founded December 2025 · Delaware C-Corporation · Dallas–Fort Worth, TX
ToxIQ™
Toxicology Revenue Intelligence
PHASE 1 · Q2 2026

AI-driven denial prevention and appeal automation for urine drug screening (G0480–G0483) and definitive drug testing (80300–80377 CPT codes). Highest-volume denial segment for independent labs.

Medical necessity validation per payer LCD
Quantity limits & frequency checking
Presumptive-to-definitive bundling compliance
Automated appeal brief generation
STATUS: Architecture complete  |  DFW pilot outreach active  |  Primary Phase 1 module
MolecuIQ™
Molecular Diagnostics & Precision RCM
PHASE 1 · PRIMARY

Full MolDX/DEX Z-code automation, CPT mapping for 75,000+ genetic tests, NGS prior authorization, and PGx claims processing. The most complex and highest-value billing module in lab medicine.

MolDX DEX Z-code assignment automation
PGx prior auth management all payers
NGS NCCN guideline alignment checking
AI appeal with clinical evidence citations
STATUS: Architecture complete  |  Primary flagship module  |  DFW molecular labs targeted Q2 2026
PulmoIQ™
Pulmonary & Respiratory Intelligence
CURRENT FOCUS

Longitudinal asthma & COPD intelligence for chronic respiratory care — follows the patient over time and keeps pulmonary-function and sleep-study documentation aligned with coding.

Reasons against GOLD (COPD) & GINA (asthma) guidelines
PFT & sleep-study coding-integrity checks
Longitudinal respiratory timeline & air-quality triggers
STATUS: Current focus area  |  Chronic & respiratory segment
Aria
Elder Care Companion
CURRENT FOCUS

A warm, voice-first companion for older adults — medication and check-in support, a safety red-flag check, and emergency escalation to 911. Pairs with the Cadence movement model.

C-SSRS red-flag safety check · 911 escalation
Medicare CCM · RPM · TCM care-coordination
Cadence movement model — 95.45% held-out (UCI HAR)
STATUS: Current focus area  |  Elder care segment
Meridian
PAMA Rate-Cliff Model
LIVE · IN-BROWSER

A deterministic model of the CLFS rate cliff — enter your test mix and forecast the 2027–2029 PAMA cuts (up to 15%/yr) and the revenue at risk. Runs entirely in the browser, no PHI.

PAMA CLFS 2027–2029 compounding cuts (≤15%/yr)
$10k/day reporting-penalty exposure check
2025 CLFS public CMS rates · no PHI
STATUS: Live calculator  |  Independent labs · reimbursement
Lumen
Report & Scan Explainer
PATIENT-FACING

Reads a lab report, discharge summary, or MRI/X-ray report and explains what stands out and what can be done — in plain language, never a diagnosis. It explains the report text, not the image itself.

Plain-language rubric · non-diagnostic policy
Flags what stands out + questions for your clinician
De-identified first by the Sentinel kernel
STATUS: Demo  |  Patient-facing explainer
🎯 Try the Platform — Interactive Demo Available Now

Explore how Ardia's models reason over denials — policy matching, MAC LCD cross-reference, and evidence-backed appeal drafting. A mobile companion is on the roadmap.

Book a Demo PLG Sandbox
🏢
Company
Ardia Precision Health, Inc.
Delaware C-Corporation
📅
Founded
December 2025
DFW Pilot · Q2 2026
📍
Headquarters
Dallas–Fort Worth, TX
Dallas-Fort Worth Metro
☁️
Infrastructure
Google Cloud Platform
Vertex AI · Healthcare Data Engine

Ardia Precision Health, Inc.  ·  ardiahealthlabs.com  ·  info@ardiahealthlabs.com  ·  Pre-Revenue · Seed Stage · Building on Google Cloud

Leadership Team

Meet the Team

Two founders who engineered and operated inside the payer systems Ardia is built to navigate — with a CEO driving strategy, partnerships and growth across precision medicine, molecular diagnostics, the PAMA rate cliff, pulmonary care and elder care.

Founder & Principal AI / Data Architect
Sole technical builder · creator of TARA

Creator of the TARA reasoning framework. 15+ years in enterprise IT with 9+ in healthcare engineering — Software Engineering Lead at Cigna, Senior SDE at Teladoc, Senior Software Developer at ECFMG, plus UnitedHealth Group / Optum — building inside the payer systems that generate denials.

MJ
Manasa Jampani
Co-Founder

10+ years across UnitedHealth Group, Interwell Health and ECFMG — inside the payer and health-services operations that decide coverage and manage care. She grounds Ardia’s product direction and go-to-market in real-world clinical and reimbursement workflows.

PK
Paramesh Kurapati
Chief Executive Officer

A practicing veterinary doctor, Paramesh leads business strategy, go-to-market, partnerships and investor relations — bringing a clinical and scientific lens to how Ardia builds governed, non-diagnostic AI for healthcare.

Board: Sireesha Mamillapalli, Ph.D. — Assistant Professor of Biochemistry & Physiology, Geisinger Commonwealth School of Medicine, bringing scientific rigor to our validation methodology.  ·  Full team & story →

See the Engine in Action

Concept: interactive dashboard showing a modelled denial analysis, MAC LCD cross-reference, and recovery narrative generation.

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